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Thermo Fisher Scientific Cyclin G1 Polyclonal Antibody
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Cyclin G1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 최적화되어 있습니다. Human 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 핵 내 Cyclin G1 검출용으로 연구용에 적합합니다.
- 카탈로그번호
- 500-10684
- 판매단위
- pk
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마지막 업데이트 2025. 08. 05. 오후 12:31
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Thermo Fisher Scientific 500-10684 Cyclin G1 Polyclonal Antibody 100 ug pk판매 단위 pk ·
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421,400원VAT 포함 463,540원
Thermo Fisher Scientific · Thermo Fisher Scientific Cyclin G1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the C-terminal of human Cyclin G1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: MCF7
- Cellular location: Nuclear
Target Information
Cyclins are regulatory subunits of Cdc2 p34 and related cyclin-dependent kinases (Cdks), which play key roles in controlling cell cycle progression.
- Cyclin A and B form complexes with Cdc2 p34 kinase to regulate G2–M and S phase transitions.
- G1–S transition is controlled by G1 cyclins such as Cyclin D1, which associates with Cdk2, Cdk4, and Cdk5.
- Cyclin E interacts with Cdk2 during the G1–S transition.
- Cyclin G contains an N-terminal cyclin box and a C-terminal domain homologous to the tyrosine phosphorylation site of the epidermal growth factor receptor.
- Cyclin G expression is induced within 3 hours after growth stimulation and remains elevated without apparent cell cycle dependency.
- Cyclin G2 shares 53% sequence identity with Cyclin G1, with peak expression in late S phase, whereas Cyclin G1 expression is constitutive.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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