Thermo Fisher Scientific Phospho-OPRD1 (Ser363) Polyclonal Antibody
Phospho-OPRD1 (Ser363) 폴리클로날 항체로, 인간, 생쥐, 랫트 시료에 반응합니다. Western blot, IHC, ELISA에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 기반 버퍼에 보관되며, 신경계 관련 연구에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (IHC) | 1:100–1:300 |
| ELISA | 1:5,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human DOR-1 around the phosphorylation site of S363 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2608829 |
Product Specific Information
This antibody is predicted to react with mouse and rat based on sequence homology.
Target Information
OPRD1 (Opioid Receptor Delta 1) is involved in the regulation of anxiety, depression, and pain. It is a potential therapeutic target for mood disorders and drug addiction. Delta and kappa opioid receptors can form heterodimers, functioning synergistically. OPRD1 is primarily expressed in the brain, with high expression in the cortex, caudate, hippocampus, nucleus accumbens, and putamen, and lower expression in the cerebellum, hypothalamus, substantia nigra, and thalamus. Reduced expression has been observed in the putamen and amygdala of Alzheimer's patients and in the putamen in Parkinson’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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