Thermo Fisher Scientific Phospho-MAP2K4 (Ser257) Polyclonal Antibody
Phospho-MAP2K4 (Ser257) 폴리클로날 항체로, 인산화된 MAP2K4 단백질 검출에 적합합니다. Western blot 및 ELISA에 사용 가능하며, 인간, 마우스, 랫트 반응성을 보입니다. 고순도 친화 크로마토그래피 정제, -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphorylated peptide around S257 of human MAP2K4 (NP_0030011) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.59 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901804 |
Product Specific Information
- Positive Samples: HeLa
- Immunogen Sequence: VDSIA
Target Information
MAP2K4 (MEK4) serine/threonine kinase (mitogen-activated protein kinase 4) MEK4 or MKK4 is a dual specificity kinase of the STE7 family that phosphorylates and activates JNK1 and JNK2 as well as p38.
MAP2K4 preferentially phosphorylates the tyrosine residue of JNKs.
MAP2K4 mediates various physiological and pathophysiological processes such as responses to cellular stresses and inflammatory cytokines.
MAP2K4 is important for carcinogenesis; a loss-of-function mutation in MAP2K4 was found in lung and pancreatic tumors. Conversely, a pro-oncogenic role was also found for MAP2K4.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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