Thermo Fisher Scientific Phospho-MEK1 (Ser217) Polyclonal Antibody
Phospho-MEK1 (Ser217) 특이적 Rabbit Polyclonal Antibody로, 인간 MEK1 단백질 인산화 상태 검출에 적합. Western blot 및 ELISA에 사용 가능. 고순도 Affinity chromatography 정제, 안정적 PBS/glycerol 저장용액 구성. 연구용 전용 시약.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphorylated peptide around S217 of human MEK1 (NP_0027461) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.14 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901801 |
Product Specific Information
- Positive Samples: HeLa
- Immunogen sequence: IDSMA
Target Information
MAP2K1 (MEK1) kinase is a dual-specificity protein kinase that functions in mitogen-activated protein kinase (MAPK) cascades, controlling cell growth and differentiation.
MAP2K1 is activated by a wide variety of growth factors and cytokines and also by membrane-dependent depolarization and calcium influx.
MEK1 is activated by phosphorylation of serine 218 and 222 residues by Raf1. It is known to be involved in signaling during stress response, apoptosis, and proliferative induction by cytokines.
Mutations in the gene can lead to cardiofaciocutaneous syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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