Thermo Fisher Scientific Phospho-KIF20A (Tyr869) Polyclonal Antibody
KIF20A Tyr869 인산화 형태를 특이적으로 인식하는 rabbit polyclonal antibody. Western blot 및 IHC(P)에서 검증됨. 고순도 정제 및 안정적 PBS/glycerol buffer 구성. 세포분열 관련 연구용으로 적합.
- 카탈로그번호
- PA5105438
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human KIF20A (Accession O95235), corresponding to amino acid residues around phosphorylated Tyr869 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816866 |
Product Specific Information
Antibody detects endogenous levels of KIF20A only when phosphorylated at Tyr869.
Target Information
Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with GTP-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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