Thermo Fisher Scientific TICAM1 Monoclonal Antibody (OTI1G7), TrueMAB
인간 TICAM1 단백질(aa 120-420)을 항원으로 제작된 마우스 단클론 항체입니다. Western blot에 최적화되어 있으며, 농도 1 mg/mL로 동결건조 상태로 제공됩니다. PBS(8% 트레할로스) 완충액에 보관하며, -20°C에서 보존이 권장됩니다.
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Applications
- Western Blot (WB): 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 120–420 of human TICAM1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
TICAM1 (TRIF) is involved in innate immune responses against pathogens. It acts as an adapter for TLR3 and TLR4 (via TICAM2) to mediate NF-κB and IRF activation, leading to apoptosis induction. Upon ligand binding, TRIF recruits effector proteins TBK1, TRAF6, and RIPK1, activating transcription factors IRF3, IRF7, NF-κB, and FADD.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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