Thermo Fisher Scientific Phospho-SMAD3 (Ser423, Ser425) Monoclonal Antibody (S.434.0)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

View 3 publications 3 publications

Immunoprecipitation (IP)

1:50

-

ChIP assay (ChIP)

1:100

View 1 publication 1 publication

Gel Shift (GS)

-

View 1 publication 1 publication

Miscellaneous PubMed (Misc)

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Monoclonal

Type

Antibody

Clone

S.434.0

Immunogen

Synthetic phosphopeptide corresponding to residues surrounding pSer423/425 of Smad3

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1387 µg/mL

Purification

Affinity chromatography

Storage buffer

0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol

Contains

<0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_11001598

Product Specific Information

It is not recommended to aliquot this antibody.

This antibody is not cross-reactive with other family members.

Target Information

SMAD3 belongs to the SMAD family of proteins. They are similar to the gene products of the Drosophila gene mothers against decapentaplegic (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.