Thermo Fisher Scientific CD3d Recombinant Rabbit Monoclonal Antibody (138)

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:1,000

Immunoprecipitation (IP)

• Tested Dilution: 0.2–1 µL/mg of lysate

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide (final concentration 0.05%–0.1%) to avoid contamination.

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. Antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal candidates.
Advantages include:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulation
• Broader immunoreactivity due to larger rabbit immune repertoire

This antibody specifically recognizes Human CD3D/CD3 Delta.

Target Information

CD3d is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The CD3d protein represents the delta subunit of the CD3 complex, which, along with other CD3 subunits, binds TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on T-cell surfaces.
Defects in the CD3d gene can cause severe combined immunodeficiency (SCIDBNK). Two transcript variants encoding different isoforms have been identified, though additional variants may exist.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.