Thermo Fisher Scientific Phospho-PNK (Ser114, Thr118) Polyclonal Antibody
인간 PNK 단백질의 인산화 부위(Ser114, Thr118)를 인식하는 폴리클로날 항체. Western blot에 적합하며 항원 친화 크로마토그래피로 정제됨. 보존제 무첨가 액상 형태로 -20°C에서 보관. DNA 손상 복구 연구용에 적합.
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Applications
- Western Blot (WB): 1:1,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide corresponding to residues around pSer114 and pThr118 of human PNK1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.01M HEPES (pH 7.5), 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10985762 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
Anti-human Polynucleotide Kinase (PNK) antibody recognizes a 57 kDa nuclear enzyme involved in DNA strand repair during replication, recombination, or in response to DNA damage. PNK acts on DNA 5'-hydroxy and 3'-phosphate termini for phosphorylation and dephosphorylation, and associates with nuclear proteins to prepare DNA ends for DNA polymerase-β and DNA ligase III. PNK is essential for maintaining genetic stability in human cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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