Thermo Fisher Scientific KIR2DL4 Polyclonal Antibody
KIR2DL4 단백질을 검출하기 위한 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등 다양한 응용 가능. 인간과 랫트 반응성. 고순도 Affinity chromatography 정제, 액상 형태로 안정적 보관 가능.
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- PA5115470
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- pk
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Thermo Fisher Scientific KIR2DL4 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human KIR2DL4 (Accession Q99706), corresponding to amino acid residues F78–L128 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900106 |
Product Specific Information
This antibody detects endogenous levels of total KIR2DL4.
Target Information
CD158d / KIR2DL4 is a member of the KIR family that shares structural features with both activating and inhibitory receptors, potentially mediating different functions depending on context.
It contains a cytoplasmic ITIM domain suggesting inhibitory function, but also a transmembrane domain similar to activating KIRs.
CD158d acts as an inhibitory receptor for peripheral and uterine NK cells; however, its ligation with soluble monoclonal antibodies (unlike immobilized ones) can activate IFN-gamma secretion.
It binds both the membrane-bound and soluble forms of its ligand HLA-G.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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