Thermo Fisher Scientific CDK5 Monoclonal Antibody (OTI2H6), TrueMAB
CDK5 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot, ICC/IF, Flow cytometry에 사용 가능. 인간 및 개에서 반응하며, 고순도 친화 크로마토그래피 정제. 동결건조 형태로 안정적이며 연구용으로 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2H6 |
| Immunogen | Full length human recombinant protein of human CDK5 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve an antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
CDK5 is a member of the cyclin-dependent kinase family, predominantly expressed in the mammalian brain. The active form, also known as neuronal cdc2-like kinase, forms a heterodimer with a 25 kDa protein derived from a 35 kDa neuron-specific precursor. CDK5 plays a critical role in neuronal migration during CNS development and phosphorylates various substrates involved in cellular processes such as adhesion, motility, synaptic plasticity, and drug addiction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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