Thermo Fisher Scientific ABHD4 Polyclonal Antibody
Human ABHD4 단백질을 인식하는 Goat Polyclonal Antibody로, WB 및 IHC(P) 검증 완료. 0.5 mg/mL 농도의 액상 형태이며, TBS buffer에 0.5% BSA 포함. 연구용으로 N-acyl ethanolamine 생합성 관련 연구에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3.75 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-RPTNPSEIRAP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2932948 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:4,000.
Target Information
The α/β hydrolase superfamily consists of diverse members involved in important biochemical processes and various diseases. Despite having unrelated sequences and different catalytic activities, they share the canonical α/β hydrolase fold with an eight-stranded parallel α/β structure and a catalytic triad of histidine, acid, and nucleophile.
Members of this superfamily are often drug targets for diseases such as diabetes, Alzheimer’s disease, obesity, and blood clotting disorders.
- ABHD1: Metabolizes smoking xenobiotics
- ABHD2: Participates in atherosclerosis development
- ABHD4: Involved in N-acyl ethanolamine (NAE) synthesis, acting as a lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE)
- ABHD5: Mutations contribute to Chanarin-Dorfman syndrome
- ABHD6: May play a role in nervous system metabolism and signaling
- ABHD14A: Possibly involved in granule neuron development
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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