Thermo Fisher Scientific Factor XIII A Polyclonal Antibody
Human Factor XIII A 단백질을 인식하는 Goat Polyclonal Antibody로, IHC(P)에서 3–6 µg/mL로 사용 가능. 0.5 mg/mL 농도의 액상 형태이며, TBS(pH 7.3) + 0.5% BSA, 0.02% sodium azide 포함. -20°C에서 보관하며, 연구용으로만 사용.
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 3–6 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-TSVHLFKERWDTNK |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2932945 |
Product Specific Information
This antibody is tested in Peptide ELISA with an antibody detection limit dilution of 1:32,000.
Target Information
This gene encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, while the B subunits may serve as plasma carrier molecules. Platelet factor XIII is composed of 2 A subunits identical to those of plasma origin. Upon cleavage by thrombin and in the presence of calcium ions, plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze crosslinking between fibrin molecules, stabilizing the fibrin clot. It also crosslinks alpha-2-plasmin inhibitor or fibronectin to the alpha chains of fibrin. Factor XIII deficiency can result in bleeding tendency, defective wound healing, and habitual abortion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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