
Thermo Fisher Scientific SLC25A5 Polyclonal Antibody
인간, 생쥐, 랫트에서 반응하는 SLC25A5 폴리클로날 항체로 Western blot에 최적화됨. 합성 펩타이드 기반 면역원 사용. 액상 형태, 1 mg/mL 농도, PBS 버퍼와 글리세롤 포함. 미토콘드리아 내막의 ADP/ATP 교환 연구에 적합.
- 카탈로그번호
- PA5118902
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SLC25A5 (Accession P05141), corresponding to amino acid residues R80–F130 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903402 |
Product Specific Information
Antibody detects endogenous levels of total SLC25A5.
Target Information
Adenine nucleotide translocator (ANT) and the voltage-dependent anion-selective channel proteins 1 and 2 (VDAC1 and VDAC2) are components of the permeability transition pore complex (PTPC) of the mitochondrial inner and outer membranes, respectively.
Formation of PTPCs, the subsequent dissipation of mitochondrial inner membrane potential, and release of cytochrome c through the outer mitochondrial membrane are critical events in the early stages of apoptosis.
Bax, a proapoptotic protein, acts upon ANT to induce the dissipation of mitochondrial inner membrane potential.
ANT1 plays a role in the maintenance of mitochondrial DNA by catalyzing the exchange of ADP and ATP across the mitochondrial inner membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-118902_SLC25A5_P05141-1_Rabbit.svg, PA5-118902_SLC25A5_P05141-1_Rabbit_PDP.jpeg)
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