Thermo Fisher Scientific RPL14 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

Antibody detects endogenous levels of total RPL14.

Target Information

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together, these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins.
This gene encodes a ribosomal protein that is a component of the 60S subunit and belongs to the L14E family of ribosomal proteins. It contains a basic region-leucine zipper (bZIP)-like domain and is located in the cytoplasm.
This gene contains a trinucleotide (GCT) repeat tract whose length is highly polymorphic; these triplet repeats result in a stretch of alanine residues in the encoded protein. Transcript variants utilizing alternative polyA signals and alternative 5′-terminal exons exist but all encode the same protein.
As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
References:
Aoki M., Diabetes 45:157–164 (1996).
Tanaka M., Biochem. Biophys. Res. Commun. 243:531–537 (1998).
Yoshihama M., Genome Res. 12:379–390 (2002).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.