Thermo Fisher Scientific PI3K p85 Recombinant Rabbit Monoclonal Antibody (7W7L10)
PI3K p85 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot과 ELISA에 적합합니다. 인간 및 생쥐 시료에 반응하며, 고순도의 Protein A 정제 항체입니다. 안정적인 액상 형태로 -20°C에서 보관 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 7W7L10 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 400–500 of human PI3 Kinase p85 alpha/beta |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.32 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
Product Specific Information
Immunogen Sequence:
SVVELINHYR NESLAQYNPK LDVKLLYPVS KYQQDQVVKE DNIEAVGKKL HEYNTQFQEK SREYDRLYEE YTRTSQEIQM KRTAIEAFNE TIKIFEEQCQ T
Target Information
Phosphatidylinositol 3-kinase (PIK3) is a signaling protein that phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. Signaling is initiated when upstream tyrosine kinase receptors or G protein-coupled receptors are bound by their ligands. It binds to activated (phosphorylated) protein-Tyr kinases through its SH2 domain and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and mutations in this gene have been associated with insulin resistance. During insulin stimulation, it also binds to IRS-1. Mutations in the gene can result in Agammaglobulinemia 7, SHORT syndrome, or Immunodeficiency 36.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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