Thermo Fisher Scientific Phospho-PKC alpha/beta-2 (Thr638, Thr641) Recombinant Rabbit Monoclonal Antibody (8D8L5)
PKC alpha/beta-2의 Thr638/Thr641 인산화 상태를 검출하는 재조합 래빗 모노클로날 항체. Western blot 및 ELISA에 적합하며 높은 특이성과 재현성을 제공. HEK293 세포 발현, Protein A 정제, 액상 형태로 안정적 보관 가능.
- 카탈로그번호
- MA555521
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:7,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 8D8L5 |
| Immunogen | A synthetic phosphorylated peptide around T638 of human PRKCA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.69 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
Target Information
Protein Kinase C alpha (PKC alpha) is a 77 kDa member of the conventional PKC group (cPKCs: sensitive to calcium, diacylglycerol, phosphatidylserine, and phorbol esters). These kinases are involved in various physiological processes such as mitogenesis, cell survival, and transcriptional regulation. PKC alpha regulates cellular functions including proliferation, differentiation, migration, adhesion, and solute transport. Phosphorylation at threonine 497 by PDK1 enables autophosphorylation at threonine 638, which is critical for PKC alpha dephosphorylation and inactivation control.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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