Thermo Fisher Scientific DRD1 Polyclonal Antibody

Applications

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1–5 µg/mL

ELISA

• Tested Dilution: Assay-dependent

Product Specifications

Product Specific Information

• Percent identity with other species by BLAST analysis:
  • 100%: Human, Gorilla, Gibbon, Monkey, Marmoset, Elephant, Rabbit
  • 93%: Mouse, Rat, Sheep, Bat, Bovine, Hamster, Panda, Pig, Opossum
• For IHC(P), use heat-induced antigen retrieval in pH 6.0 citrate buffer.
  After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

Target Information

The D1 subtype is the most abundant dopamine receptor in the central nervous system.
This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases.
D1 receptors regulate neuronal growth and development, mediate behavioral responses, and modulate dopamine receptor D2-mediated events.
Alternate transcription initiation sites result in two transcript variants of this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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