Thermo Fisher Scientific DPP9 Polyclonal Antibody

Applications

Immunohistochemistry (Paraffin) [IHC (P)]

• Tested Dilution: 10 µg/mL

Product Specifications

Product Specific Information

• Percent identity with other species by BLAST analysis:
  Human, Gibbon, Marmoset, Mouse, Bovine, Dog, Horse (100%);
  Hamster, Panda (94%);
  Bat, Elephant, Turkey, Chicken (88%);
  Gorilla, Opossum (81%).

• For IHC(P), use heat-induced antigen retrieval in pH 6.0 citrate buffer.
  After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

Target Information

This gene encodes a protein that is a member of the S9B family in clan SC of the serine proteases.
The protein exhibits post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins.
Although similar in activity to dipeptidyl peptidase 4 (DPP4), it is not membrane bound.
Dipeptidyl peptidases are involved in regulating substrate activity and have been linked to diseases such as type 2 diabetes, obesity, and cancer.
Several transcript variants have been described but not fully characterized.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.