Thermo Fisher Scientific DRD3 Polyclonal Antibody
DRD3 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. IHC 및 ELISA에 사용 가능하며, 인간 DRD3의 세포질 도메인 펩타이드로부터 제작됨. 냉장 또는 -20°C 장기 보관 가능. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 20 µg/mL |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human DRD3 (Dopamine Receptor D3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 1 month. For long-term storage, store at -20°C. |
| Shipping Conditions | Wet ice |
| RRID | AB_2550199 |
Product Specific Information
- In IHC applications, antigen retrieval using a citrate buffer (pH 6.0) is recommended.
- Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Monkey, Marmoset (100%).
Target Information
This gene encodes the D3 subtype of the five (D1–D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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