Thermo Fisher Scientific APRIL Monoclonal Antibody (Aprily-1)
인간 APRIL 단백질을 인식하는 마우스 단클론 항체로, WB 및 유세포분석에 사용 가능. 정제된 액상 형태로 1 mg/mL 농도 제공. PBS 완충액 및 0.02% sodium azide 포함. 4°C 보관, 연구용 한정.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2 µg/mL |
| Flow Cytometry (Flow) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | Aprily-1 |
| Immunogen | Recombinant fragment corresponding to residues 93–233 of human APRIL, expressed in bacteria |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Purified |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_779285 |
Product Specific Information
MA1-25839 will not react with mouse.
Target Information
Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified and designated APRIL (A Proliferation-Inducing Ligand), TALL2 (TNF and ApoL-related Leukocyte-expressed Ligand 2), and TRDL1a (TNF-related death ligand 1a) in human and mouse.
Two receptors for APRIL were recently identified and designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-κB, and induces cell death.
APRIL and its close relative BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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