Thermo Fisher Scientific THRAP3 Polyclonal Antibody
THRAP3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF에 사용 가능. 고순도 항원 친화 크로마토그래피 정제. 인간 반응성, 액상 형태, 장기 보관 시 -20°C 권장.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human THRAP3. Recombinant protein control fragment (Product #RP-89453) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2648445 |
Product Specific Information
Immunogen sequence:
ETEEREESTT GFDKSRLGTK DFVGPSERGG GRARGTFQFR ARGRGWGRGN YSGNNNNNSN NDFQKRNREE EWDPEYTPKS KKYYLHDDRE GEGSDKWVSR GRGRGAFPRG RGRFMFRKSS TSPKWAHDKF S
Highest antigen sequence identity to the following orthologs:
- Mouse: 95%
- Rat: 95%
Target Information
THRAP3 is a 955 amino acid nuclear receptor-associated protein and a member of the Thyroid hormone receptor-associated proteins. It contains a LISH domain and functions as a 150 kDa subunit of the TRAP complex, contributing to the structure of the fibrillar center and dense fibrillar component in the nucleolus.
THRAP3 plays a role in transcriptional coactivation and interacts with DKC1, NOP5/NAP65, and fibrillarin. Northern blot analysis indicates that TRAP150 is ubiquitously expressed across human tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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