Thermo Fisher Scientific THRAP3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human THRAP3. Recombinant protein control fragment (Product #RP-89453). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:THRAP3,uniProtId:Q9Y2W1-1,ncbiNodeId:9606,antigenRange:798-928,antigenLength:955,antigenImageFileName:PA5-52898_THRAP3_Q9Y2W1-1_Rabbit.svg,antigenImageFileNamePDP:PA5-52898_THRAP3_Q9Y2W1-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2648445

Product Specific Information

Immunogen sequence: ETEEREESTT GFDKSRLGTK DFVGPSERGG GRARGTFQFR ARGRGWGRGN YSGNNNNNSN NDFQKRNREE EWDPEYTPKS KKYYLHDDRE GEGSDKWVSR GRGRGAFPRG RGRFMFRKSS TSPKWAHDKF S

Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.

Target Information

THRAP3 is a 955 amino acid novel nuclear receptor and a member of the Thyroid hormone receptor associated proteins with a LISH domain and no obvious known sequence motifs. THRAP3 is a 150 kDa subunit of the large multiprotein complex TRAP and is important in the maintenance of the fundamental structure of the fibrillar center and dense fibrillar component in the nucleolus. It is also known to play an important role in transcriptional coactivation. It is known to interact with DKC1, nop5/nap65 and fibrillarin. From the Northern blot analysis of several human tissues it was found that TRAP150 is ubiquitously expressed.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.