
Thermo Fisher Scientific OXCT1 Polyclonal Antibody
OXCT1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로널 항체로, 인간·마우스·랫에서 반응합니다. Western blot, IHC, ICC/IF에 사용 가능하며, 고순도 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로 안정적 저장 및 재현성 높은 결과를 제공합니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human OXCT1. Recombinant protein control fragment (Product #RP-88730). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.60 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645131 |
Product Specific Information
Immunogen sequence:
VGGFGLCGIP ENLIDALLKT GVKGLTAVSN NAGVDNFGLG LLLRSKQIKR MVSSYVGENA EFERQYLSGE LEVELTPQGT LAERIRAGGA GVPAFYTPTG YGTLVQEGGS PIKYNKDGSV AIASKPREVR EFNGQHFILE EAITGDF
Antigen sequence identity:
- Mouse: 97%
- Rat: 96%
Target Information
The OXCT1 gene encodes a member of the 3-oxoacid CoA-transferase family. The encoded protein is a homodimeric mitochondrial matrix enzyme central to extrahepatic ketone body catabolism, catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate.
Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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