Thermo Fisher Scientific CHD4 Polyclonal Antibody
Human CHD4 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC, ICC/IF, ChIP 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 연구용으로만 사용 가능.
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Thermo Fisher Scientific CHD4 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
| ChIP assay (ChIP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CHD4. Recombinant protein control fragment (Product #RP-102496). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2639758 |
Product Specific Information
Immunogen sequence:
DALLNNSLPP PHPENEEDPE EDLSETETPK LKKKKKPKKP RDPKIPKSKR QKKELGDSSG EGPEFVEEEE EVALRSDSEG SDYTPGKKKK KKLGPKKEKK SKSKRKEEEE EDDDDDDSKE P
Highest antigen sequence identity to orthologs:
- Mouse: 97%
- Rat: 96%
Target Information
The CHD4 gene product is a member of the SNF2/RAD54 helicase family and a core component of the nucleosome remodeling and deacetylase complex. It plays a critical role in epigenetic transcriptional repression. Autoantibodies against CHD4 are found in patients with dermatomyositis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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