Thermo Fisher Scientific CYP4F11 Polyclonal Antibody
Human CYP4F11 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF에 사용 가능. Affinity chromatography로 정제된 액상 항체이며, 고순도와 높은 특이성을 제공. 연구용으로 약물 대사 및 P450 효소 연구에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CYP4F11 (Accession Q9HBI6), corresponding to amino acid residues I427–E477 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851450 |
Product Specific Information
Antibody detects endogenous levels of total Cytochrome P450 4F11.
Target Information
Cytochrome P450 proteins (CYPs) are monooxygenases that catalyze reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids.
CYP4F11 is an isoform of the cytochrome P450 4F protein, expressed mainly in human liver, followed by kidney, heart, and skeletal muscle. It contains 524 amino acid residues and shares high sequence identity with CYP4F2, CYP4F3, and CYP4F8.
CYP4F11 has catalytic properties toward endogenous eicosanoids and certain drugs, capable of metabolizing large molecules such as erythromycin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-102019_CYP4F11_Q9HBI6-1_Rabbit_PDP.jpeg)
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