Thermo Fisher Scientific Skeletal Muscle Actin Polyclonal Antibody
Rabbit polyclonal antibody targeting human skeletal muscle actin. Suitable for Western blot applications. Purified by antigen affinity chromatography. Supplied in PBS buffer with glycerol and thimerosal. For research use only.
- 카탈로그번호
- PA5117283
- 판매단위
- pk
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Thermo Fisher Scientific Skeletal Muscle Actin Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human alpha Skeletal Muscle Actin (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.11 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901913 |
Product Specific Information
- Centrifuge briefly prior to opening.
Target Information
The gene encoded by this product belongs to the actin family of proteins, which are highly conserved and play a key role in cell motility, structure, and integrity. Alpha, beta, and gamma actin isoforms have been identified:
- Alpha actins: Major constituents of the contractile apparatus
- Beta and gamma actins: Involved in the regulation of cell motility
This antibody targets alpha actin found in skeletal muscle. Mutations in this gene are associated with:
- Nemaline myopathy type 3
- Congenital myopathy with excess thin myofilaments
- Congenital myopathy with cores
- Congenital myopathy with fiber-type disproportion
These conditions lead to muscle fiber defects.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information: www.P65Warnings.ca.gov
Usage Note
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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