Thermo Fisher Scientific Phospho-STING (Ser366) Polyclonal Antibody
Human STING 단백질의 Ser366 위치 인산화 상태를 인식하는 Rabbit Polyclonal 항체. Western blot 및 ELISA에 적합하며, 고순도 친화 크로마토그래피로 정제됨. 액상 형태로 제공되며 -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphorylated peptide around S366 of human STING/TMEM173 (NP_9380231) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.08 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901906 |
Product Specific Information
- Positive Samples: THP-1
- Immunogen Sequence: LISGME
Target Information
STING is a 379-amino-acid signaling protein that acts as a key component of innate immune signaling. It activates NF-kappa-B and IRF3 transcription pathways, inducing type I interferons (IFN-alpha and IFN-beta) and promoting an antiviral state. STING may also function as a translocon, influencing interferon induction and apoptotic signal transduction via MHC-II association. It is localized in the endoplasmic reticulum membrane, cell membrane, and mitochondrial outer membrane, and is ubiquitously expressed across most tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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