Thermo Fisher Scientific SDHB Monoclonal Antibody (CL0349)
인간 SDHB 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Western blot, IHC, ICC/IF에 적합합니다. 단백질 A로 정제된 액상 형태이며, 안정한 PBS/glycerol buffer에 보존됩니다. 미토콘드리아 복합체 II 연구에 활용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 2–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CL0349 |
| Immunogen | Recombinant protein corresponding to Human SDHB (UniProt ID: P21912-1, antigen range: 165–273, antigen length: 280) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2786987 |
Product Specific Information
Immunogen sequence:
EGKQQYLQSI EEREKLDGLY ECILCACCST SCPSYWWNGD KYLGPAVLMQ AYRWMIDSRD DFTEERLAKL QDPFSLYRCH TIMNCTRTCP KGLNPGKAIA EIKKMMATY
Target Information
Complex II of the respiratory chain is involved in the oxidation of succinate, transferring electrons from FADH to CoQ. It consists of four nuclear-encoded subunits localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters that form the enzyme’s iron-sulfur centers. Mutations in this gene are associated with paragangliomas and pheochromocytoma, linking mitochondrial dysfunction to tumorigenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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