
Thermo Fisher Scientific Kappa Light Chain (B-Cell Marker) Polyclonal Antibody
인간 Kappa Light Chain을 인식하는 Rabbit Polyclonal 항체로, B세포 마커 분석에 사용됩니다. IHC(P)에서 2–10 µg/mL로 적용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 백혈병, 형질세포종, 림프종 연구에 유용합니다.
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) [IHC (P)]: 2–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Immunoglobulin kappa light chain |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive Control: Tosil
- Cellular Location: Secreted
Target Information
Immunoglobulin classes share a basic structure of four polypeptide chains: two heavy chains (five types) and two light chains (kappa, lambda; both ~22.5 kDa).
Kappa and lambda chains each have variable and constant regions, differentiated by antigenic properties of the constant region.
The normal ratio of kappa to lambda is approximately 70:30.
Antibodies to the kappa light chain are useful in identifying leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas.
Demonstration of clonality in lymphoid infiltrates indicates malignancy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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