Thermo Fisher Scientific Insulin Monoclonal Antibody (2D11H5)
인슐린 단백질을 인식하는 마우스 모노클로날 항체로, IHC(P) 및 ELISA에 적합합니다. 인간, 돼지, 쥐 시료에 반응하며, 비결합형 액상 형태로 제공됩니다. 단기 4°C, 장기 -20°C 보관이 권장됩니다.
- 카탈로그번호
- 500-1774
- 판매단위
- pk
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Applications and Tested Dilution
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2–10 µg/mL
ELISA
- Tested Dilution: 0.01–0.1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Pig, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2D11H5 |
| Immunogen | Insulin Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive Control: Pancreas
- Cellular Location: Cytoplasmic
Target Information
Insulin is a peptide hormone secreted by beta cells of the pancreatic islets. It regulates carbohydrate, protein, and lipid metabolism by enhancing membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids.
Insulin is a 51-amino acid polypeptide produced from a precursor peptide, proinsulin. Proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds and one molecule of C-peptide.
Insulin deficiency results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of β-cell origin such as insulinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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