Thermo Fisher Scientific B7-H4 (Immuno-Inhibitory Protein) Recombinant Rabbit Monoclonal Antibody (B7H4, 2652R)
인간 B7-H4 단백질을 표적으로 하는 Thermo Fisher Scientific의 재조합 래빗 모노클로날 항체입니다. IHC, ICC/IF, Flow Cytometry 등 다양한 응용에 적합하며, 고순도 Protein A/G 정제 및 안정적 PBS 버퍼로 제공됩니다. 암 연구 및 면역조절 메커니즘 분석에 유용합니다.
- 카탈로그번호
- 79679-RBM2-P0
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific B7-H4 (Immuno-Inhibitory Protein) Recombinant Rabbit Monoclonal Antibody (B7H4, 2652R)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | B7H4, 2652R |
| Immunogen | Recombinant fragment of human B7-H4 protein (amino acids 32–147) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 min at room temperature.
- Formalin-fixed tissue staining requires heating sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 min at 95°C, followed by cooling at room temperature for 20 min.
Target Information
B7-H4 (also known as B7x, VTCN1) is a costimulatory protein functioning as a negative regulator of T-cell mediated immunity.
It delivers inhibitory signals to T-cells, preventing proliferation, cell cycle progression, and interleukin-2 production.
B7-H4 is expressed on activated T-cells, B-cells, monocytes, and dendritic cells, and aberrant expression is associated with lung, breast, and ovarian cancers.
Overexpression may enable tumor cells to suppress T-cell immunity, facilitating tumor progression.
VTCN1 may serve as a biomarker for early detection of ovarian cancer and renal cell carcinoma (RCC).
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 없음, OCR 텍스트만 통합됨)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.