Thermo Fisher Scientific ADNP Polyclonal Antibody
ADNP 단백질을 인식하는 Thermo Fisher Scientific의 Goat Polyclonal 항체입니다. Western blot, IHC, ICC 등 다양한 응용에 사용 가능하며, Mouse 및 Rat 시료에 반응합니다. 항원 친화 크로마토그래피로 정제되었으며, 동결건조 형태로 제공됩니다.
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- PA547792
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | 5–15 µg/mL | – |
| Immunocytochemistry (ICC/IF) | 5–15 µg/mL | – |
| CUT&RUN (C&R) | – | – |
Product Specifications
| Category | Specification |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived recombinant mouse ADNP (Leu941–Ala1102) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2576251 |
Product Specific Information
- In direct ELISAs, approximately 30% cross-reactivity with recombinant human ADNP is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Vasoactive intestinal peptide (VIP) is a neuroprotective factor that influences tumor cell growth—stimulating some and inhibiting others. The ADNP gene encodes a protein upregulated by VIP, potentially mediating its stimulatory effects on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, indicating a role as a transcription factor. It is also upregulated in proliferative tissues and may enhance cell viability via modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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