Thermo Fisher Scientific Leptin Polyclonal Antibody
Leptin 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 다양한 면역학적 응용(IHC, ICC, Flow, ELISA)에 사용 가능. 고순도 Protein A 정제, 1 mg/mL 농도, -20°C 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from mouse Leptin, amino acids 101–154 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Leptin is a 167 amino acid protein hormone (~16 kDa) encoded by the obese (ob) gene. It plays a key role in regulating body weight, metabolism, and reproductive function. Leptin is mainly produced by adipocytes, reflecting total body fat mass. It is also secreted by stomach epithelium and placenta cells. Leptin receptors are abundant in the hypothalamus, T lymphocytes, and endothelial cells, mediating effects on hunger, thermogenesis, and energy expenditure. Leptin influences hematopoiesis, angiogenesis, wound healing, inflammation, immune responses, pubertal development, and fetal growth. Dysregulation of leptin is associated with obesity, anorexia nervosa, insulin resistance, and hypertension.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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