Thermo Fisher Scientific Mouse IgG1 Isotype Control (MOPC-21)
Mouse IgG1 아이소타입 대조항체로 다양한 면역실험(WB, IHC, ICC, Flow, ELISA 등)에 사용 가능. MOPC-21 클론 기반의 단클론 항체이며 비특이적 반응 검증용 음성 대조로 적합. PBS 용액 형태, 4°C 보관, 단백질 A 정제.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Flow Cytometry (Flow) | Assay-dependent |
| ELISA | Assay-dependent |
| Immunoprecipitation (IP) | Assay-dependent |
| Functional Assay | Assay-dependent |
| Control (Ctrl) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Isotype Control |
| Clone | MOPC-21 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2536775 |
Available Conjugated Formats
Product Specific Information
This mouse IgG1 kappa monoclonal antibody (clone MOPC-21) has unknown specificity and serves as a reliable negative control for experiments involving human and rat tissues. It has been validated across multiple assays to confirm its suitability as an isotype control.
Target Information
Mouse IgG1 is a subtype of immunoglobulin G produced by B cells in response to antigens. It is the most abundant IgG subclass in serum and plays a critical role in the adaptive immune response. Structurally, it consists of two heavy and two light chains and participates in:
- Opsonization
- Complement activation
- Antibody-dependent cell-mediated cytotoxicity (ADCC)
- Regulation of immune responses, including T cell activation and B cell inhibition
Mouse IgG1 is widely used in research and diagnostic applications such as ELISA, Western blotting, and immunohistochemistry, as well as in therapeutic research including immunotherapy and vaccine development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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