Thermo Fisher Scientific Phospho-Parathyroid Hormone Receptor 1 (Ser501, Thr503, Ser504) Polyclonal Antibody
인간 PTH1R의 Ser501, Thr503, Ser504 인산화 부위에 특이적인 폴리클로날 항체. Western blot에 최적화되어 있으며, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 제공되며, 단기 4°C, 장기 -20°C 보관 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human PTH1 around the phosphorylation site of Ser501/Thr503/Ser504 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Parathyroid hormone receptor 1 (PTH1R) is a member of the G-protein coupled receptor family. It acts as a receptor for parathyroid hormone (PTH) and parathyroid hormone-like hormone (PTHLH). The receptor mediates signaling through G proteins that activate adenylyl cyclase and a phosphatidylinositol-calcium second messenger system.
Defects in this receptor are associated with Jansen’s metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), and enchondromatosis. PTH1R expression has been reported in bone, breast, brain, colon, GI tract, kidney, liver, placenta, skin, umbilical cord, and uterus.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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