Thermo Fisher Scientific SPIN1 Polyclonal Antibody
SPIN1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunohistochemistry(Paraffin)에 적합하며, 고순도(>95%) 항체. 인간, 마우스, 랫트 반응성. 연구용으로 세포주기 조절 관련 단백질 분석에 활용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 1 publication |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | View publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 110–156 of human Spindlin-1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553492 |
Product Specific Information
This antibody detects endogenous SPIN1 protein at a molecular weight of approximately 30 kDa.
Purity is >95% by SDS-PAGE.
Target Information
SPIN1 (Spindlin 1), also known as SPIN or ovarian cancer-related protein (OCR), is a 262 amino acid nuclear protein involved in regulation of the cell cycle during the transition from gamete to embryo.
A member of the SPIN/STSY family, SPIN1 localizes to the interphase nucleus and mitotic chromosomes and is phosphorylated in a cell-cycle-dependent manner. Overexpression of SPIN1 can cause mitotic spindle defects, leading to chromosome instability and potential tumorigenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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