Thermo Fisher Scientific Prohibitin (Mitochondrial Marker) Monoclonal Antibody (PHB/3225)
Prohibitin 단백질을 인식하는 Thermo Fisher Scientific의 미토콘드리아 마커 단일클론 항체. Western blot, IHC, ICC 등 다양한 응용에 사용 가능. 인간 시료 반응성, Mouse IgG2b 형식, 고순도 Protein A/G 정제. 연구용으로만 사용.
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- 5245-MSM5-P1ABX
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Thermo Fisher Scientific Prohibitin (Mitochondrial Marker) Monoclonal Antibody (PHB/3225)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
| Immunomicroscopy (IM) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PHB/3225 |
| Immunogen | Recombinant human PHB protein fragment (aa167–261) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Prohibitin is an evolutionarily conserved gene that is ubiquitously expressed. It is thought to act as a negative regulator of cell proliferation and may function as a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated regions. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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