Thermo Fisher Scientific Prohibitin (Mitochondrial Marker) Monoclonal Antibody (PHB/3225)
Prohibitin 단백질을 표적하는 Thermo Fisher Scientific의 미토콘드리아 마커 단일클론 항체. Western blot, IHC, ICC 등 다양한 응용에 적합. 인간 시료 반응성, 단일클론(Mouse IgG2b) 형태, 액상 상태로 제공. 연구용 한정 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
| Immunomicroscopy (IM) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PHB/3225 |
| Immunogen | Recombinant human PHB protein fragment (aa167–261) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Prohibitin is an evolutionarily conserved gene that is ubiquitously expressed. It is believed to act as a negative regulator of cell proliferation and may function as a tumor suppressor. Mutations in the PHB gene have been associated with sporadic breast cancer. Prohibitin is expressed as two transcripts differing in the length of their 3′ untranslated region. The longer transcript is found at higher levels in proliferating tissues and cells, suggesting that this region may serve as a trans-acting regulatory RNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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