Thermo Fisher Scientific Dicer Polyclonal Antibody
Dicer 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunoprecipitation에 적합합니다. 인간 Dicer1의 1175–1225번 잔기 영역을 면역원으로 제작되었습니다. 액상 형태이며 4°C에서 보관, 1년의 권장 유효기간을 가집니다.
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Applications and Tested Dilution
| Application | Tested Dilution / Amount |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 5–15 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1175 and 1225 of human double-stranded RNA-specific endoribonuclease Dicer1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Dicer is a double-stranded RNA (dsRNA) endoribonuclease that plays a central role in short dsRNA-mediated post-transcriptional gene silencing. It cleaves long dsRNAs and short hairpin pre-microRNAs (miRNA) into 21–23 nucleotide fragments with 3′ overhangs, generating short interfering RNAs (siRNA) and mature microRNAs (miRNA).
These small RNAs guide the RNA-induced silencing complex (RISC) to complementary RNAs for degradation or translational repression.
RNA interference (RNAi) mediated by siRNAs regulates the removal of transcripts from mobile or repetitive DNA elements and degradation of exogenous viral RNAs. The miRNA pathway specifically regulates target gene expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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