Thermo Fisher Scientific Dicer Polyclonal Antibody
Dicer 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot 및 Immunoprecipitation에 적합합니다. 인간 Dicer1의 600–650번 잔기 영역을 면역원으로 사용하였으며, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- A301936Ax (2개 옵션)
- 판매단위
- pk
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2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Dicer Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 600 and 650 of human double-stranded RNA-specific endoribonuclease, Dicer1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Dicer is a double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. It cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of 21–23 nucleotides with a 3′ overhang of two nucleotides, producing short interfering RNAs (siRNA) and mature microRNAs.
SiRNAs and miRNAs guide the RNA-induced silencing complex (RISC) to complementary RNAs for degradation or translational repression.
RNA interference (RNAi) mediated by siRNAs regulates the elimination of transcripts from mobile and repetitive DNA elements and the degradation of exogenous viral RNA. The miRNA pathway specifically regulates expression of target genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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