Thermo Fisher Scientific STAT2 Polyclonal Antibody
STAT2 단백질을 표적으로 하는 Rabbit Polyclonal 항체로, WB, IHC, IP 등 다양한 응용에 적합합니다. 액상 형태로 제공되며 4°C에서 보관합니다. 인간 STAT2(801-851 aa) 영역을 면역원으로 사용하였으며 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution / Amount |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 801 and 851 of Human Signal Transducer and Activator of Transcription 2 (STAT2, UniProt ID: P52630-3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections.
Target Information
STAT2 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by receptor-associated kinases and form homo- or heterodimers that translocate to the nucleus to act as transcription activators.
In response to interferon (IFN), STAT2 forms a complex with STAT1 and IFN regulatory factor p48 (ISGF3G), acting as a transactivator but lacking direct DNA-binding ability. Transcription adaptor P300/CBP (EP300/CREBBP) interacts specifically with STAT2 and is involved in blocking IFN-alpha response by adenovirus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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