Thermo Fisher Scientific LOX Polyclonal Antibody
LOX 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. Western blot, IHC, ICC 등 다양한 응용에 적합하며, 인간·마우스·랫 종에서 검증되었습니다. Rat LOX 단백질의 특정 펩타이드(150–200, 275–325)를 면역원으로 사용합니다. 연구용으로만 제공됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:4,000 | View 5 publications |
| Immunohistochemistry (IHC) | - | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:250 | View publications |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-Dependent | View publications |
| Immunocytochemistry (ICC/IF) | Assay-Dependent | View publications |
Product Specifications
| Specification | Description |
|---|---|
| Published Species | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Two synthetic peptides (residues 150–200 and 275–325) of the rat LOX protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet Ice |
| RRID | AB_2134926 |
Target Information
Lysyl oxidase (LOX) is a copper-containing amine oxidase belonging to a heterogeneous family of enzymes that oxidize primary amine substrates to reactive aldehydes. It plays a crucial role in the formation and repair of the extracellular matrix. LOX is multifunctional, involved in developmental regulation, tumor suppression, cell motility, and cellular senescence. The secreted form of LOX contributes to the invasive properties of hypoxic human cancer cells, making it essential for hypoxia-induced metastasis and a potential therapeutic target for preventing and treating metastases.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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