Thermo Fisher Scientific IRF7 Recombinant Rabbit Monoclonal Antibody (SC0617)
IRF7 단백질을 표적으로 하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체입니다. Western blot, IHC, ICC/IF, Flow Cytometry 등 다양한 응용에 적합합니다. 높은 특이성과 재현성을 제공하며, 연구용으로만 사용됩니다.
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Thermo Fisher Scientific IRF7 Recombinant Rabbit Monoclonal Antibody (SC0617)
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000–1:5,000 | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | - |
| Flow Cytometry (Flow) | 1:100 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SC0617 |
| Immunogen | Synthetic peptide within human IRF7 (aa 200–240) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 0.05% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2898919 |
Target Information
Interferons (IFNs) are involved in multiple immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms. During infection, host-virus interactions signal downstream molecules such as transcription factors like IFN regulatory factor-3 (IRF3), which stimulate transcription of IFN-α/β genes. IRF7 plays a key role in transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. It interacts with Toll-like receptor (TLR) adaptor proteins MyD88 and Tirp/TRAM, functioning as an intermediate in TLR4 and TLR9 signaling. There are at least four differentially spliced isoforms of IRF7, though their functions are not clearly established.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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