Thermo Fisher Scientific CDC6 Monoclonal Antibody (OTI8E6), TrueMAB
인간 CDC6 단백질을 인식하는 마우스 단클론 항체로, Western blot에 최적화되어 있습니다. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능합니다. DNA 복제 개시 조절 연구에 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8E6 |
| Immunogen | Full length human recombinant protein of human CDC6 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The CDC6 protein is a regulator essential for the initiation of DNA replication. It localizes to the nucleus during the G1 phase of the cell cycle and translocates to the cytoplasm at the start of the S phase.
This translocation is regulated by phosphorylation through Cdks.
Transcription of CDC6 is controlled by mitogenic signals via E2F transcription factors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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