Thermo Fisher Scientific PAX3 Recombinant Rabbit Monoclonal Antibody (16H22L10)

Applications and Tested Dilution

Product Specifications

Product Specific Information

• This antibody is predicted to react with mouse based on sequence homology.
• Intact IgG appears on a non-reducing gel as ~150 kDa band and upon reduction generates a ~25 kDa light chain band and a ~50 kDa heavy chain.
• Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits.
• Advantages include:
  • Better specificity and sensitivity
  • Lot-to-lot consistency
  • Animal origin-free formulations
  • Broader immunoreactivity due to the large rabbit immune repertoire

Target Information

Pax 3 (Paired Box 3) is a transcription factor involved in the development of the peripheral nervous system, melanocytes, vascular smooth muscle, and other derivatives. It regulates neurogenesis in pre-migratory neural crest cells from the dorsal neural tube and in myogenic progenitors in the presomitic mesoderm and hypaxial somites.
Alternative splicing results in isoforms with different C-termini.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.