Thermo Fisher Scientific H3K36me1 Recombinant Rabbit Monoclonal Antibody (1F4)
H3K36me1 타겟에 특이적인 재조합 토끼 모노클로날 항체(클론 1F4). Western blot 및 면역세포염색에 적합. 인간 시료 반응성. 고순도 친화 크로마토그래피 정제. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:30–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 1F4 |
| Immunogen | A synthesized peptide corresponding to H3K36me1 (UniProt ID: P68431-1, antigen range: 35–39, antigen length: 136) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.35 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 150 mM NaCl |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2898200 |
Product Specific Information
This antibody has been tested in direct-ELISA.
Target Information
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3, along with four core histone proteins, binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication, and chromosomal stability. Post-translational modifications of histones can directly alter chromatin structure or mediate the binding of transcription factors. The N-terminal tail of histone H3 can undergo methylation, acetylation, or phosphorylation, influencing various cellular processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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