Thermo Fisher Scientific CCR1 Polyclonal Antibody, Biotin
CCR1 단백질을 인식하는 Biotin 결합 토끼 다클론 항체로, Western blot, IHC, ELISA, IP 등 다양한 응용에 적합합니다. 마우스와 랫트 반응성이 있으며, 고순도의 친화 크로마토그래피 정제 제품입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide taken within amino acid region 1–50 on mouse CCR1 protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Chemokines play important roles in inflammation and are critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein–coupled receptors. The chemokine receptor subtypes are divided into two major groups, CXCR and CCR.
CCR1, one of the CCR receptors, is expressed on neutrophils, monocytes, lymphocytes, and eosinophils, and binds macrophage-inflammatory protein (MIP-1), eotaxin, and other related chemokines.
Mice lacking CCR1 show defects in neutrophil trafficking and proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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