Thermo Fisher Scientific CCR1 Polyclonal Antibody, Biotin
Human CCR1 단백질을 인식하는 Biotin 결합 Rabbit Polyclonal 항체로, Western blot, ELISA, Immunoprecipitation에 적합합니다. 고순도 Affinity chromatography로 정제되었으며, 안정적인 액상 형태로 연구용으로 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide taken within amino acid region 1–50 on human CCR1 protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Chemokines play important roles in inflammation and are critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein–coupled receptors. The chemokine receptor subtypes can be divided into two major groups, CXCR and CCR.
CCR1, one of the CCR receptors, is expressed on neutrophils, monocytes, lymphocytes, and eosinophils and binds macrophage-inflammatory protein (MIP-1), eotaxin, and other related chemokines.
Mice lacking CCR1 show defects in neutrophil trafficking and proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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