Thermo Fisher Scientific IFN-Alpha Polyclonal Antibody
인간, 마우스, 랫트 반응성을 가진 IFN-Alpha 폴리클로날 항체. 다양한 어세이(WB, IHC, ICC, ELISA)에 적용 가능. 단백질 A 정제, 고순도 액상 형태. 면역원은 Mouse IFNA1 유래 합성 펩타이드. 연구용으로만 사용.
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Thermo Fisher Scientific IFN-Alpha Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from Mouse IFNA1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
IFN alpha (Interferon alpha) is a Type I interferon belonging to a family of structurally related, species-specific proteins exclusive to vertebrates. The interaction of IFN-alpha with its receptor components activates several signaling pathways involved in innate immune responses against viral infections.
In humans, the IFN alpha gene is located on chromosome 9. Type I interferons include 14 alpha isoforms and single beta, omega, epsilon, and kappa isoforms. Homologous molecules are found in many species, including rats, mice, birds, reptiles, and fish. IFN alpha is produced primarily by plasmacytoid dendritic cells and plays a key role in antiviral innate immunity and modulation of adaptive immunity.
Diseases associated with IFN alpha dysfunction include Hepatitis C and Hepatitis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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