Thermo Fisher Scientific Marburg Virus VP40 Monoclonal Antibody (3542)

Applications

Tested Dilution

Publications

ELISA (ELISA)

1:20-1:200

-

Product Specifications

Species Reactivity

Virus

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

3542

Immunogen

Proprietary sequence

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

100 µg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.2

Contains

0.1% sodium azide

Storage conditions

4° C

Shipping conditions

Wet ice

RRID

AB_2942484

Product Specific Information

Specificity: Specific for the VP40 antigen of the virus. Reactive with several native strains. Negative for EBOLA. Non-reactive with mammalian cells (ICC/IF).

Purified preparations consist of >90% pure mouse monoclonal antibody which has been purified from ascites fluid by protein A chromatography. The final preparation is formulated to a protein concentration of 100 µg/mL in 0.01 M phosphate buffered saline, pH 7.2 and contains 0.1% sodium azide. Each vial contains 1.0 ml. This product contains no stabilizing proteins and should be stored at 4C until ready for use. Working dilution must be determined by the user. Suggested starting ranges are 1:10-1:50 for ICC/IF and 1:20-1:200. for ELISA.

Target Information

Marburg virus (MBG) is a representative of Filoviridae family of RNA containing viruses. MBG is an exceptionally dangerous pathogen, which induces a severe contagious and highly lethal (53-88%) febrile disease with hemorrhagic syndrome. The name thread viruses is based on their morphology. MBG made its appearance in 1967 in the form of frightening nosocomial outbreak, initially among polio vaccine production workers in Germany in contact with Ugandan green monkeys and their kidney tissues. The patho-and immuno-genesis of MBG fever have so far been little studied, no specific agents or treatment methods have been developed. VP40 is essential for assembly and release of newly copied viruses and also suppresses immune signaling in the infected cell.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.